Zhong-Yuan Xia Selected Research

Glucose (Dextrose)

7/2023	Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus.
12/2022	Role of CK1ε-regulated PERIOD2 in STZ-induced diabetic myocardial injury.
1/2022	The Protective Role of Bmal1-Regulated Autophagy Mediated by HDAC3/SIRT1 Pathway in Myocardial Ischemia/Reperfusion Injury of Diabetic Rats.
9/2019	The Pathway of Let-7a-1/2-3p and HMGB1 Mediated Dexmedetomidine Inhibiting Microglia Activation in Spinal Cord Ischemia-Reperfusion Injury Mice.
1/2019	Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro.
1/2019	Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes.
1/2019	Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling.
2/2018	Neuroprotective effect of bispectral index-guided fast-track anesthesia using sevoflurane combined with dexmedetomidine for intracranial aneurysm embolization.
8/2017	(-)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions.
6/2017	DJ-1 overexpression restores ischaemic post-conditioning-mediated cardioprotection in diabetic rats: role of autophagy.

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Zhong-Yuan Xia Research Topics

Disease

18	Reperfusion Injury 07/2023 - 12/2004
14	Hypoxia (Hypoxemia) 07/2023 - 01/2016
14	Ischemia 01/2020 - 12/2004
13	Myocardial Ischemia (Ischemic Heart Diseases) 07/2023 - 01/2011
6	Hyperglycemia 08/2021 - 01/2013
6	Lung Injury 03/2019 - 02/2012
5	Wounds and Injuries (Trauma) 12/2022 - 04/2011
5	Myocardial Infarction 01/2022 - 01/2011
5	Cognitive Dysfunction 11/2020 - 03/2018
4	Necrosis 06/2023 - 02/2012
4	Infarction (Infarctions) 11/2022 - 10/2011
4	Inflammation (Inflammations) 11/2020 - 12/2017
3	Diabetes Mellitus 07/2023 - 01/2016
3	Neoplasms (Cancer) 01/2022 - 01/2017
3	COVID-19 01/2021 - 01/2020
3	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 06/2012
3	Acute Lung Injury 01/2018 - 02/2012
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 08/2014
2	Sepsis (Septicemia) 08/2021 - 11/2018
2	Neuroinflammatory Diseases 07/2020 - 01/2019
2	Hemorrhagic Shock 03/2019 - 01/2018
2	Cardiomegaly (Heart Hypertrophy) 10/2016 - 08/2014
2	Pulmonary Edema 02/2012 - 06/2009
1	Dizziness (Lightheadedness) 01/2023
1	Glioma (Gliomas) 01/2022
1	Atrophy 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2020
1	Thrombocytopenia (Thrombopenia) 10/2020
1	Pain (Aches) 07/2020
1	Chronic Pain 07/2020
1	Hypotension (Low Blood Pressure) 01/2020
1	Postoperative Pain 01/2020
1	Spinal Cord Ischemia 09/2019

Drug/Important Bio-Agent (IBA)

15	Glucose (Dextrose)FDA LinkGeneric 07/2023 - 08/2014
7	Proteins (Proteins, Gene)FDA Link 03/2019 - 06/2009
5	Propofol (Diprivan)FDA LinkGeneric 11/2019 - 07/2011
5	AntioxidantsIBA 01/2019 - 01/2013
4	salicylhydroxamic acid (SHAM)IBA 11/2022 - 01/2011
4	Streptozocin (Streptozotocin)FDA Link 01/2022 - 10/2011
4	InflammasomesIBA 01/2019 - 01/2016
4	Heme Oxygenase-1IBA 10/2016 - 06/2009
4	Caspase 3 (Caspase-3)IBA 08/2014 - 12/2004
3	LipopolysaccharidesIBA 08/2021 - 11/2018
3	Anesthetics (Anesthetic Agents)IBA 01/2020 - 08/2014
3	Oxygen (Dioxygen)IBA 09/2019 - 01/2011
3	Dexmedetomidine FDA Link 09/2019 - 02/2018
3	Remifentanil (Ultiva)FDA Link 01/2019 - 11/2018
3	Sevoflurane (Ultane)FDA LinkGeneric 01/2019 - 02/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 12/2004
3	ginsenoside Rb1IBA 06/2012 - 01/2011
2	histone deacetylase 3IBA 01/2022 - 01/2019
2	Sirtuin 1IBA 01/2022 - 08/2017
2	Isoflurane FDA LinkGeneric 11/2020 - 07/2011
2	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 01/2020 - 01/2019
2	Long Noncoding RNAIBA 11/2019 - 01/2017
2	honokiolIBA 01/2019 - 01/2019
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2019 - 01/2019
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 02/2012
2	8-epi-prostaglandin F2alphaIBA 01/2019 - 08/2014
2	Lactic Acid (Lactate)FDA LinkGeneric 02/2018 - 08/2017
2	penehyclidineIBA 01/2018 - 02/2012
2	Peroxidase (Myeloperoxidase)IBA 01/2018 - 02/2012
2	Malondialdehyde (Propanedial)IBA 09/2017 - 08/2014
2	Fentanyl (Sublimaze)FDA LinkGeneric 01/2017 - 07/2011
1	GlycolipidsIBA 07/2023
1	nobiletinIBA 07/2023
1	IronIBA 06/2023
1	Hypertonic Glucose SolutionIBA 01/2023
1	erastinIBA 11/2022
1	ferrostatin-1IBA 11/2022
1	radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA 11/2022
1	SR9009IBA 10/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	trans-crotonin (CTN)IBA 01/2022
1	U 0126 (UO 126)IBA 01/2022
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2022
1	Caveolin 3IBA 08/2021
1	Protein Isoforms (Isoforms)IBA 08/2021
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021
1	TensinsIBA 01/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	GlucocorticoidsIBA 01/2021
1	Inhalation AnestheticsIBA 11/2020
1	ProcalcitoninIBA 10/2020
1	Troponin IIBA 10/2020
1	Glucagon-Like Peptide-1 ReceptorIBA 07/2020
1	Exenatide (Byetta)FDA Link 07/2020
1	4,5-dianilinophthalimideIBA 01/2020

Therapy/Procedure

9	Ischemic Postconditioning 01/2021 - 06/2009
2	General Anesthesia 01/2023 - 01/2020
2	Intraperitoneal Injections 01/2022 - 10/2017
2	Ligation 07/2020 - 07/2018
2	Anesthesia 01/2019 - 02/2018
1	Intravenous Administration 01/2023
1	Aftercare (After-Treatment) 07/2020
1	Modified Radical Mastectomy (Mastectomy, Modified) 01/2020
1	Epidural Anesthesia 01/2020
1	Artificial Respiration (Mechanical Ventilation) 01/2020
1	Patient Transfer (Patient Dumping) 01/2020